Developmental Gene and Neuroanatomical Mechanisms of Risk

Dell Medical School's Department of Psychiatry presents Developmental Gene and Neuroanatomical Mechanisms of Risk: Bipolar Disorder, Comorbid Substance Use, and Vulnerability to Suicidal Behavior by Dr Elizabeth Lippard.

Clinical outcomes in Bipolar Disorder are highly heterogeneous and treatment and prevention strategies are currently limited by our inability to identify inter-individual differences (e.g. genetic and neuroanatomical) that may be related to risk for particular outcomes, such as problems with addiction or suicide-related behavior. Addiction and suicide are highly prevalent in Bipolar Disorder, yet not all individuals with the disorder will suffer from addiction or suicide-related behavior. Work to be presented will include cross-sectional and longitudinal work employing multimodal magnetic resonance imaging aimed at understanding genetic, neuroanatomical, and sex differences in adolescents/young adults with Bipolar Disorder that are associated with risk for, and transitions to, substance use problems and suicide-related behavior. Preclinical data utilizing multimodal imaging in transgenic rodent models will also be discussed.    

Dr. Elizabeth Lippard is a postdoctoral fellow in the Mood Disorders Research Program at Yale University. She completed her graduate training in neurobiology from the University of North Carolina, Chapel Hill. She has cross-trained in both human and animal models: studying both psychiatric disorders and behavior and investigating brain-behavior relationships, in human and rodent models, across development, and how genes and environmental insults influence these processes. She is highly articulate and has been doing pioneering longitudinal work at Yale employing multimodal magnetic resonance imaging in adolescents/young adults with Bipolar Disorder and in the context of early life stress and applying these same approaches to preclinical transgenic rodent models. Her research aims to disentangle mechanisms underlying risk with mechanisms associated with transitions to detrimental outcomes (i.e. suicide and addiction) within and across psychiatric disorders.

Tuesday, June 7, 2016 at 10:00am to 11:00am

Peter O'Donnell Jr. Building (POB), Avaya Auditorium, POB 2.302
201 24TH ST E, Austin, Texas 78712

Event Type

Academics

Departments

Dell Medical School

Target Audience

Students, Faculty

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