The Briscoe Center's exhibit, Greatest Hits, features unique treasures and highlights from the center's extensive collection of primary sources related to music and the music industry. From early folk songs to stadium rock, Greatest Hits displays photographs, posters, artifacts, sheet music, original correspondence and music industry records, as well as a variety of audio visual resources at listening stations. These resources provide access to the many diverse traditions, creative processes, performances, and recordings that comprise the history of American music.

The Briscoe Center has long emphasized music as part of its mission to document the historical experience of the American people. The center's music collections and resources embrace many different types of folk and popular music cultivated in Texas, the greater South and Southwest, and beyond. They also help document the development of the music industry and some of the forces that shape how music is created, discovered, performed, and broadcast.